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Proteinase Activated Receptor 3 (F2RL2) Antibody
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Catalogue No: abx026701
Price:
US$326.25
(Size: 80 µl)
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Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.
Research Articles on Proteinase Activated Receptor 3 (F2RL2)
| Target | Proteinase Activated Receptor 3 (F2RL2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human F2RL2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O00254 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R754, B4DQ13, Q52M68, Q7Z3W3 |
| UniProt Entry Name | PAR3_HUMAN |
| Gene Symbol | F2RL2 |
| KEGG | hsa:2151 |
| String | 9606.ENSP00000296641 |
| Molecular Weight | Calculated MW: 42.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |