Fibrinogen Gamma (FGG) Antibody

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains.Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots.In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.Alternative splicing results in two transcript variants encoding different isoforms.

Target	Fibrinogen Gamma (FGG)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC, IF/ICC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human FGG expressed in E. coli.
Isotype	IgG2a
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P02679 (UniProt, ExPASy)
UniProt Entry Name	FIBG_HUMAN
Gene Symbol	FGG
GeneID	2266
OMIM	134850
HGNC	3694
KEGG	hsa:2266
Ensembl	ENSG00000171557
String	9606.ENSP00000336829
Molecular Weight	52 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fibrinogen Gamma (FGG)

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