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Histone Cluster 2, H2aa3 (HIST2H2AA3) Antibody
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Catalogue No: abx027547
Price:
US$326.25
(Size: 80 µl)
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Research Articles on Histone Cluster 2, H2aa3 (HIST2H2AA3)
| Target | Histone Cluster 2, H2aa3 (HIST2H2AA3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 2-30 amino acids from the N-terminal region of human HIST2H2AA3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q6FI13 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5F0, P20670 |
| UniProt Entry Name | H2A2A_HUMAN |
| KEGG | hsa:723790 hsa:8337 |
| String | 9606.ENSP00000475814 |
| Molecular Weight | Calculated MW: 14.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Chicken, Monkey and C. elegans H2AC18. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |