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High Mobility Group Protein B1 (HMGB1) Antibody
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Catalogue No: abx029495
Price:
US$326.25
(Size: 80 µl)
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DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V (D) J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
Research Articles on High Mobility Group Protein B1 (HMGB1)
| Target | High Mobility Group Protein B1 (HMGB1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 152-180 amino acids from the C-terminal region of human HMGB1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09429 (UniProt, ExPASy) |
| UniProt Secondary AC | A5D8W9, Q14321, Q5T7C3, Q6IBE1 |
| UniProt Entry Name | HMGB1_HUMAN |
| KEGG | hsa:3146 |
| String | 9606.ENSP00000345347 |
| Molecular Weight | Calculated MW: 24.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Pig, Hamster, Horse and Monkey HMGB1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |