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Mitogen-Activated Protein Kinase-Binding Protein 1 (MAPKBP1) Antibody
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Catalogue No: abx002043
Price:
US$203.00
(Size: 20 µl)
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MAPKBP1 Antibody is a Rabbit Polyclonal antibody against MAPKBP1. MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
Research Articles on Mitogen-Activated Protein Kinase-Binding Protein 1 (MAPKBP1)
| Target | Mitogen-Activated Protein Kinase-Binding Protein 1 (MAPKBP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPKBP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60336 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NM93, A8K8P9, Q14CB5, Q14CD8, Q49AJ8, Q5W9G9 |
| UniProt Entry Name | MABP1_HUMAN |
| Gene Symbol | MAPKBP1 |
| GeneID | 23005 |
| NCBI Accession | NP_001122080.1 |
| KEGG | hsa:23005 |
| String | 9606.ENSP00000393099 |
| Molecular Weight | Calculated MW: 164 kDa Observed MW: 164 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |