Natriuretic Peptides A (NPPA) Antibody

Natriuretic Peptides A (NPPA) Antibody is a Rabbit Polyclonal antibody for the detection of NPPA.

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.

Target	Natriuretic Peptides A (NPPA)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	natriuretic peptide precursor A
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P01160 (UniProt, ExPASy)
UniProt Secondary AC	Q13766, Q5JZE1
UniProt Entry Name	ANF_HUMAN
Gene Symbol	NPPA
GeneID	4878
OMIM	108780
HGNC	7939
KEGG	hsa:4878
Ensembl	ENSG00000175206
String	9606.ENSP00000365663
Molecular Weight	Observed MW: 17 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Natriuretic Peptides A (NPPA)

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