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Serpin Family E Member 1 (SERPINE1) Antibody
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Catalogue No: abx012034
Price:
US$420.50
(Size: 100 µl)
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This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Serpin Family E Member 1 (SERPINE1)
| Target | Serpin Family E Member 1 (SERPINE1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human SERPINE1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P05121 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z4S0, F8WD53 |
| UniProt Entry Name | PAI1_HUMAN |
| Gene Symbol | SERPINE1 |
| GeneID | 5054 |
| OMIM | 173360 |
| HGNC | 8583 |
| KEGG | hsa:5054 |
| Ensembl | ENSG00000106366 |
| String | 9606.ENSP00000223095 |
| Molecular Weight | 45 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |