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Sphingomyelin Phosphodiesterase (SMPD1) Antibody
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Catalogue No: abx026668
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a lysosomal Sphingomyelin Phosphodiesterase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq].
Research Articles on Sphingomyelin Phosphodiesterase (SMPD1)
| Target | Sphingomyelin Phosphodiesterase (SMPD1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/4000, IHC-P: 1/500, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 391-419 amino acids from the C-terminal region of human SMPD1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P17405 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K8M3, E9PKS3, P17406, Q13811, Q16837, Q16841 |
| UniProt Entry Name | ASM_HUMAN |
| Gene Symbol | SMPD1 |
| GeneID | 6609 |
| OMIM | 607608 |
| HGNC | 11120 |
| KEGG | hsa:6609 |
| Ensembl | ENSG00000166311 |
| String | 9606.ENSP00000340409 |
| Molecular Weight | Calculated MW: 69.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow SMPD1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |