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UDP-Glucose 6-Dehydrogenase (UGDH) Antibody
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Catalogue No: abx026918
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.
Research Articles on UDP-Glucose 6-Dehydrogenase (UGDH)
| Target | UDP-Glucose 6-Dehydrogenase (UGDH) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human UGDH. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60701 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KUU2, B4DN25, O60589 |
| UniProt Entry Name | UGDH_HUMAN |
| Gene Symbol | UGDH |
| KEGG | hsa:7358 |
| String | 9606.ENSP00000319501 |
| Molecular Weight | Calculated MW: 55 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat UGDH. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |