72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Antibody

REQUEST MORE INFO
Catalogue No: abx003688
Price: US$232.00
(Size: 20 µl)
Reviews: 0 Publications and Reviews
(0 Publications and Reviews)

Click on the image to see the image legend

Western blot analysis of various lysates, using CD81 Rabbit antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 10s.
72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E) Antibody

Available Options

* Size:



Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
INPP5E Antibody is a Rabbit Monoclonal antibody against INPP5E. The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome; a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly.

Target 72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E)
Clonality Monoclonal
Reactivity Mouse, Rat
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/1000 - 1/6000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD81.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9NRR6 (UniProt, ExPASy)
UniProt Secondary AC Q15734, Q6PIV5
UniProt Entry Name INP5E_HUMAN
GeneID 56623
String 9606.ENSP00000360777
Molecular Weight Calculated MW: 26 kDa
Observed MW: 22 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 0.05% BSA, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on 72 kDa Inositol Polyphosphate 5-Phosphatase (INPP5E)
Tags:
(Click to show)