ATP Binding Cassette Transporter A1 (ABCA1) Antibody

ABCA1 Antibody is a Rabbit Polyclonal antibody against ABCA1. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

Target	ATP Binding Cassette Transporter A1 (ABCA1)
Clonality	Polyclonal
Reactivity	Mouse, Rat
Tested Applications	IF/ICC
Host	Rabbit
Recommended dilutions	IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1870-2120 of human ABCA1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95477 (UniProt, ExPASy)
UniProt Entry Name	ABCA1_HUMAN
Gene Symbol	ABCA1
GeneID	19
OMIM	205400
NCBI Accession	NP_005493.2
HGNC	29
KEGG	hsa:19
Ensembl	ENSG00000165029
String	9606.ENSP00000363868
Molecular Weight	Calculated MW: 254 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on ATP Binding Cassette Transporter A1 (ABCA1)

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