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ATP Binding Cassette Transporter A1 (ABCA1) Antibody
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Catalogue No: abx005455
Price:
US$348.00
(Size: 60 µl)
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ABCA1 Antibody is a Rabbit Polyclonal antibody against ABCA1. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
Research Articles on ATP Binding Cassette Transporter A1 (ABCA1)
| Target | ATP Binding Cassette Transporter A1 (ABCA1) |
| Clonality | Polyclonal |
| Reactivity | Mouse, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human ABCA1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95477 (UniProt, ExPASy) |
| UniProt Entry Name | ABCA1_HUMAN |
| Gene Symbol | ABCA1 |
| GeneID | 19 |
| OMIM | 205400 |
| NCBI Accession | NP_005493.2 |
| HGNC | 29 |
| KEGG | hsa:19 |
| Ensembl | ENSG00000165029 |
| String | 9606.ENSP00000363868 |
| Molecular Weight | Calculated MW: 254 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |