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Multidrug Resistance-Associated Protein 4 (ABCC4) Antibody
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Catalogue No: abx001810
Price:
US$348.00
(Size: 60 µl)
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ABCC4 Antibody is a Rabbit Polyclonal antibody against ABCC4. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.
Research Articles on Multidrug Resistance-Associated Protein 4 (ABCC4)
| Target | Multidrug Resistance-Associated Protein 4 (ABCC4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human MRP4 / ABCC4 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15439 (UniProt, ExPASy) |
| UniProt Secondary AC | A9Z1Z7, B7Z3Q7, Q8IVZ4, Q8IZN6, Q8NEW8, Q9Y6J2 |
| UniProt Entry Name | MRP4_HUMAN |
| Gene Symbol | ABCC4 |
| GeneID | 10257 |
| NCBI Accession | NP_005836.2 |
| KEGG | hsa:10257 |
| String | 9606.ENSP00000366084 |
| Molecular Weight | Calculated MW: 88 kDa/96 kDa/144 kDa/149 kDa Observed MW: 140-200 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
