Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 (ABCG2) Antibody

REQUEST MORE INFO
Catalogue No: abx028408
Price: US$326.25
(Size: 80 µl)
Reviews: 0 Publications and Reviews
(0 Publications and Reviews)

Click on the image to see the image legend

WB analysis of HepG2 cell lysates (35 ug/lane) using ABCG2 Antibody. Detection of ABCG2 protein shown by the arrow.
Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 (ABCG2) Antibody Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 (ABCG2) Antibody

Available Options

* Size:


Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.

Target Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 (ABCG2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/100 - 1/500, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide from the C-terminal region of Human ABCG2 (594-623 AA).
Isotype IgG
Form Liquid
Purification Purified by saturated ammonium sulfate (SAS) precipitation followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9UNQ0 (UniProt, ExPASy)
UniProt Entry Name ABCG2_HUMAN
NCBI Accession NP_001244315.1 NP_004818.2
String 9606.ENSP00000237612
Molecular Weight Calculated MW: 72.3 kDa
Buffer PBS containing 0.09% sodium azide.
Concentration 2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 (ABCG2)
Tags:
(Click to show)