ATP Binding Cassette Subfamily G Member 5 (ABCG5) Antibody
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Price:
US$420.50
(Size: 100 µl)
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols.It is expressed in a tissue-specific manner in the liver, colon, and intestine.This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8.Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
Target |
ATP Binding Cassette Subfamily G Member 5 (ABCG5) |
Clonality |
Monoclonal |
Reactivity |
Human |
Tested Applications |
ELISA, WB, FCM |
Host |
Mouse |
Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation |
Unconjugated |
Immunogen |
Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli. |
Isotype |
IgG1 |
Form |
Liquid |
Purification |
Purified from ascites by Protein G chromatography. |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
72.5 kDa |
Buffer |
PBS, containing 0.05% sodium azide. |
Concentration |
1 mg/ml |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |
Research Articles on ATP Binding Cassette Subfamily G Member 5 (ABCG5)