ATP Binding Cassette Subfamily G Member 5 (ABCG5) Antibody

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Catalogue No: abx015759
Price: US$449.50
(Size: 100 µl)

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Datasheet SDS
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols.It is expressed in a tissue-specific manner in the liver, colon, and intestine.This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8.Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.

Target ATP Binding Cassette Subfamily G Member 5 (ABCG5)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Purified from ascites by Protein G chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9H222 (UniProt, ExPASy)
UniProt Secondary AC Q2T9G2, Q96QZ2, Q96QZ3
UniProt Entry Name ABCG5_HUMAN
Gene Symbol ABCG5
GeneID 64240
OMIM 210250
HGNC 13886
Ensembl ENSG00000138075
String 9606.ENSP00000260645
Molecular Weight 72.5 kDa
Buffer PBS, containing 0.05% sodium azide.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on ATP Binding Cassette Subfamily G Member 5 (ABCG5)