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Tyrosine-Protein Kinase ABL1 (Abl1) Antibody
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Catalogue No: abx027683
Price:
US$326.25
(Size: 80 µl)
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Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
Research Articles on Tyrosine-Protein Kinase ABL1 (Abl1)
| Target | Tyrosine-Protein Kinase ABL1 (Abl1) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 613-641 amino acids from the Central region of mouse Abl1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P00520 (UniProt, ExPASy) |
| UniProt Entry Name | ABL1_MOUSE |
| Gene Symbol | ABL1 |
| GeneID | 11350 |
| KEGG | mmu:11350 |
| String | 10090.ENSMUSP00000075167 |
| Molecular Weight | Calculated MW: 123 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |