Acid-Sensing Ion Channel 3 (ACCN3) Antibody

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Catalogue No: abx030787
Price: US$326.25
(Size: 80 µl)

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Documents

Datasheet SDS
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium. Alternative splicing of this gene generates three transcript variants encoding distinct isoforms.

Target Acid-Sensing Ion Channel 3 (ACCN3)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human ACCN3.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9UHC3 (UniProt, ExPASy)
UniProt Secondary AC B2R9V0, O60263, O75906, Q59FN9, Q9UER8, Q9UHC4
UniProt Entry Name ASIC3_HUMAN
Gene Symbol ASIC3
String 9606.ENSP00000297512
Molecular Weight Calculated MW: 58.9 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Acid-Sensing Ion Channel 3 (ACCN3)


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