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Angiotensin I Converting Enzyme (ACE) Antibody
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Catalogue No: abx025482
Price:
US$623.50
(Size: 100 µl)
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This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. This antibody is supplied as crude ascites.
Research Articles on Angiotensin I Converting Enzyme (ACE)
| Target | Angiotensin I Converting Enzyme (ACE) |
| Clonality | Monoclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1274-1306 amino acids from human ACE. |
| Isotype | IgG2a |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12821 (UniProt, ExPASy) |
| UniProt Secondary AC | B0LPF0, B4DXI3, E7EU16, P22966, Q53YX9, Q59GY8, Q7M4L4 |
| UniProt Entry Name | ACE_HUMAN |
| KEGG | hsa:1636 |
| String | 9606.ENSP00000290866 |
| Molecular Weight | Calculated MW: 150 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |