Activated CDC42 Kinase 1 (ACK1) Antibody

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Catalogue No: abx033628
Price: US$326.25
(Size: 80 µl)
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Activated CDC42 Kinase 1 (ACK1) Antibody
Activated CDC42 Kinase 1 (ACK1) Antibody Activated CDC42 Kinase 1 (ACK1) Antibody Activated CDC42 Kinase 1 (ACK1) Antibody

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Datasheet SDS
ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP) stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.

Target Activated CDC42 Kinase 1 (ACK1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 934-964 amino acids from the C-terminal region of human ACK1.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q07912 (UniProt, ExPASy)
UniProt Secondary AC Q6ZMQ0, Q8N6U7, Q96H59
UniProt Entry Name ACK1_HUMAN
NCBI Accession NP_001010938.1 NP_005772.3
KEGG hsa:10188
String 9606.ENSP00000371341
Molecular Weight Calculated MW: 115 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Cow TNK2.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Activated CDC42 Kinase 1 (ACK1)
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