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Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
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Catalogue No: abx001175
Price:
US$217.50
(Size: 20 µl)
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ACSL5 Antibody is a Rabbit Polyclonal antibody against ACSL5. Acyl-CoA synthetase 5, a member of the ACSL gene family that catalyzes the activation of long-chain fatty acids for lipid biosynthesis, is the only ACSL isoform that is both, located on mitochondria and functionally involved in enterocyte apoptosis.ACSL5 could play a role in promoting fatty acid-induced lipoapoptosis in hepatocytes as important mechanism in fatty liver-related disorders(PMID:20470896). ACSL5 is most abundant in liver, brown adipose tissue, and intestine and is located on both the mitochondrial membrane and endoplasmic reticulum(PMID:20798351). It has 3 isoforms produced by alternative splicing. This antibody is specific to ACSL5.
Research Articles on Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5)
| Target | Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 500-739 of human ACSL5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9ULC5 (UniProt, ExPASy) |
| UniProt Secondary AC | A6GV77, D3DRB3, Q6UX44, Q9UIU4 |
| UniProt Entry Name | ACSL5_HUMAN |
| Gene Symbol | ACSL5 |
| GeneID | 51703 |
| NCBI Accession | NP_057318.2 |
| String | 9606.ENSP00000348429 |
| Molecular Weight | Calculated MW: 76 kDa Observed MW: 70-76 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |