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Actin, Alpha Skeletal Muscle (ACTA1) Antibody
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Catalogue No: abx028299
Price:
US$326.25
(Size: 80 µl)
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The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Research Articles on Actin, Alpha Skeletal Muscle (ACTA1)
| Target | Actin, Alpha Skeletal Muscle (ACTA1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human ACTA1/Alpha-actin. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P68133 (UniProt, ExPASy) |
| UniProt Secondary AC | P02568, P99020, Q5T8M9 |
| UniProt Entry Name | ACTS_HUMAN |
| NCBI Accession | NP_001091.1 |
| KEGG | hsa:58 |
| String | 9606.ENSP00000355645 |
| Molecular Weight | Calculated MW: 42.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Pig and Xenopus ACTA1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |