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Actin-Like Protein 6B (ACTL6B) Antibody
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Catalogue No: abx005371
Price:
US$203.00
(Size: 20 µl)
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ACTL6B Antibody is a Rabbit Polyclonal antibody against ACTL6B. The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.
Research Articles on Actin-Like Protein 6B (ACTL6B)
| Target | Actin-Like Protein 6B (ACTL6B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ACTL6B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O94805 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D2D0, O75421 |
| UniProt Entry Name | ACL6B_HUMAN |
| Gene Symbol | ACTL6B |
| GeneID | 51412 |
| NCBI Accession | NP_057272.1 |
| KEGG | hsa:51412 |
| String | 9606.ENSP00000160382 |
| Molecular Weight | Calculated MW: 47 kDa Observed MW: 47-55 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |