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Actinin Alpha 2 (ACTN2) Antibody
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Catalogue No: abx028440
Price:
US$326.25
(Size: 80 µl)
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Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles.
Research Articles on Actinin Alpha 2 (ACTN2)
| Target | Actinin Alpha 2 (ACTN2) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 751-779 amino acids from the C-terminal region of human ACTN2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35609 (UniProt, ExPASy) |
| UniProt Secondary AC | B1ANE4, B2RCS5, Q86TF4, Q86TI8 |
| UniProt Entry Name | ACTN2_HUMAN |
| Gene Symbol | ACTN2 |
| KEGG | hsa:88 |
| String | 9606.ENSP00000443495 |
| Molecular Weight | Calculated MW: 104 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow ACTN2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |