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Alpha-Centractin (ACTR1A) Antibody
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Catalogue No: abx004995
Price:
US$217.50
(Size: 20 µl)
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ACTR1A Antibody is a Rabbit Polyclonal antibody against ACTR1A. This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
Research Articles on Alpha-Centractin (ACTR1A)
| Target | Alpha-Centractin (ACTR1A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 187-376 of human ACTR1A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P61163 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R6B0, P42024 |
| UniProt Entry Name | ACTZ_HUMAN |
| Gene Symbol | ACTR1A |
| GeneID | 10121 |
| NCBI Accession | NP_005727.1 |
| KEGG | hsa:10121 |
| String | 9606.ENSP00000358921 |
| Molecular Weight | Calculated MW: 43 kDa Observed MW: 43 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |