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Activin A Receptor Type 1B (ACVR1B) Antibody
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Catalogue No: abx025223
Price:
US$326.25
(Size: 80 µl)
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This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
Research Articles on Activin A Receptor Type 1B (ACVR1B)
| Target | Activin A Receptor Type 1B (ACVR1B) |
| Clonality | Monoclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human ACVR1B recombinant protein. |
| Isotype | IgG1 Kappa |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P36896 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z5L8, B7Z5W5, Q15479, Q15480, Q15481, Q15482 |
| UniProt Entry Name | ACV1B_HUMAN |
| KEGG | hsa:91 |
| String | 9606.ENSP00000442656 |
| Molecular Weight | Calculated MW: 56.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |