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Activin A Receptor Type 2A (ACVR2A) Antibody
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Catalogue No: abx001614
Price:
US$348.00
(Size: 60 µl)
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ACVR2A Antibody is a Rabbit Polyclonal antibody against ACVR2A. This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.
Research Articles on Activin A Receptor Type 2A (ACVR2A)
| Target | Activin A Receptor Type 2A (ACVR2A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/100 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human ACVR2A |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P27037 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RAB8, B4DWQ2, D3DP85, Q53TH4, Q6NWV2, Q92474 |
| UniProt Entry Name | AVR2A_HUMAN |
| Gene Symbol | ACVR2A |
| GeneID | 92 |
| NCBI Accession | NP_001607.1 |
| KEGG | hsa:92 |
| String | 9606.ENSP00000241416 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |