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Adenosine Deaminase (ADA) Antibody
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Catalogue No: abx026363
Price:
US$326.25
(Size: 80 µl)
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This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.
Research Articles on Adenosine Deaminase (ADA)
| Target | Adenosine Deaminase (ADA) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/500, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 287-314 amino acids from the C-terminal region of human ADA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P00813 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53F92, Q6LA59 |
| UniProt Entry Name | ADA_HUMAN |
| Gene Symbol | ADA |
| NCBI Accession | NP_000013.2 |
| KEGG | hsa:100 |
| String | 9606.ENSP00000361965 |
| Molecular Weight | Calculated MW: 40.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |