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ADAM Metallopeptidase Domain 17 (ADAM17) Antibody
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Catalogue No: abx028423
Price:
US$326.25
(Size: 80 µl)
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ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Research Articles on ADAM Metallopeptidase Domain 17 (ADAM17)
| Target | ADAM Metallopeptidase Domain 17 (ADAM17) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 195-224 amino acids from the N-terminal region of human ADAM17. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS, then purified by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P78536 (UniProt, ExPASy) |
| UniProt Secondary AC | O60226 |
| UniProt Entry Name | ADA17_HUMAN |
| KEGG | hsa:6868 |
| String | 9606.ENSP00000309968 |
| Molecular Weight | Calculated MW: 93 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |