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Alpha 1B Adrenergic Receptor (ADRA1B) Antibody
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Catalogue No: abx034358
Price:
US$290.00
(Size: 80 µl)
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Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, 1B and 1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This protein encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This protein comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Research Articles on Alpha 1B Adrenergic Receptor (ADRA1B)
| Target | Alpha 1B Adrenergic Receptor (ADRA1B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 270-297 amino acids from the Central region of human ADRA1B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35368 (UniProt, ExPASy) |
| UniProt Secondary AC | B0LPE1 |
| UniProt Entry Name | ADA1B_HUMAN |
| Gene Symbol | ADRA1B |
| KEGG | hsa:147 |
| String | 9606.ENSP00000306662 |
| Molecular Weight | Calculated MW: 56.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Rabbit ADRA1B. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |