Glycogen Debranching Enzyme (AGL) Antibody

AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1, 6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.

Target	Glycogen Debranching Enzyme (AGL)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 357-387 amino acids from the Central region of human AGL.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35573 (UniProt, ExPASy)
UniProt Entry Name	GDE_HUMAN
NCBI Accession	NP_000019.2 NP_000633.2 NP_000634.2 NP_000635.2 NP_000636.2 NP_000637.2
KEGG	hsa:178
String	9606.ENSP00000294724
Molecular Weight	Calculated MW: 175 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glycogen Debranching Enzyme (AGL)

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