Anterior Gradient Protein 2 Homolog (AGR2) Antibody

Anterior gradient 2 (AGR2) is known as a cancer cell marker specifically up-regulated in response to depletion of serum and oxygen. AGR2 has been identified as a tumor marker in primary and secondary cancer lesions, and as a marker for detection of circulating tumor cells (CTCs). Elevated levels of AGR2 are known to increase the metastatic potential of cancer cells, but conditions leading to increased expression of AGR2 are not well understood.

Target	Anterior Gradient Protein 2 Homolog (AGR2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 95-124 amino acids from the Central region of human AGR2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O95994 (UniProt, ExPASy)
UniProt Entry Name	AGR2_HUMAN
Gene Symbol	AGR2
NCBI Accession	NP_006399.1
KEGG	hsa:10551
String	9606.ENSP00000391490
Molecular Weight	Calculated MW: 20 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Zebrafish AGR2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Anterior Gradient Protein 2 Homolog (AGR2)

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