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Apoptosis Inducing Factor 1, Mitochondrial (AIFM1) Antibody
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Catalogue No: abx034154
Price:
US$326.25
(Size: 80 µl)
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AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.
Research Articles on Apoptosis Inducing Factor 1, Mitochondrial (AIFM1)
| Target | Apoptosis Inducing Factor 1, Mitochondrial (AIFM1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/200, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human AIFM1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95831 (UniProt, ExPASy) |
| UniProt Entry Name | AIFM1_HUMAN |
| Gene Symbol | AIFM1 |
| KEGG | hsa:9131 |
| String | 9606.ENSP00000287295 |
| Molecular Weight | Calculated MW: 66.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |