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Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) Antibody
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Catalogue No: abx004051
Price:
US$203.00
(Size: 20 µl)
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AIMP1 Antibody is a Rabbit Polyclonal antibody against AIMP1. The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20.
Research Articles on Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1)
| Target | Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 25-180 of human AIMP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12904 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KTR2, B4E1S7, Q6FG28, Q96CQ9 |
| UniProt Entry Name | AIMP1_HUMAN |
| Gene Symbol | AIMP1 |
| GeneID | 9255 |
| NCBI Accession | NP_001135888.1 |
| KEGG | hsa:9255 |
| String | 9606.ENSP00000378191 |
| Molecular Weight | Calculated MW: 34 kDa Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |