Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Antibody

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Catalogue No: abx026368
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Target Aldo-Keto Reductase Family 1 Member C3 (AKR1C3)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 107-135 amino acids from the Central region of human AKR1C3.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P42330 (UniProt, ExPASy)
UniProt Entry Name AK1C3_HUMAN
Gene Symbol AKR1C3
NCBI Accession NP_001240837.1 NP_003730.4
KEGG hsa:8644
String 9606.ENSP00000369927
Molecular Weight Calculated MW: 36.9 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Aldo-Keto Reductase Family 1 Member C3 (AKR1C3)


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