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Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Antibody
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Catalogue No: abx026368
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Research Articles on Aldo-Keto Reductase Family 1 Member C3 (AKR1C3)
| Target | Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 107-135 amino acids from the Central region of human AKR1C3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P42330 (UniProt, ExPASy) |
| UniProt Entry Name | AK1C3_HUMAN |
| Gene Symbol | AKR1C3 |
| NCBI Accession | NP_001240837.1 NP_003730.4 |
| KEGG | hsa:8644 |
| String | 9606.ENSP00000369927 |
| Molecular Weight | Calculated MW: 36.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |