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Aldo-Keto Reductase Family 1 Member C4 (AKR1C4) Antibody
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Catalogue No: abx028769
Price:
US$290.00
(Size: 80 µl)
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AKR1C4 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Research Articles on Aldo-Keto Reductase Family 1 Member C4 (AKR1C4)
| Target | Aldo-Keto Reductase Family 1 Member C4 (AKR1C4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human AKR1C4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P17516 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5T6A3, Q8WW84, Q9NS54 |
| UniProt Entry Name | AK1C4_HUMAN |
| Gene Symbol | AKR1C4 |
| KEGG | hsa:1109 |
| String | 9606.ENSP00000369814 |
| Molecular Weight | Calculated MW: 37.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |