+44 (0) 1223 755950
+1 832 327 7413
RAC-Gamma Serine/threonine-Protein Kinase (Akt3) Antibody
REQUEST MORE INFO
Catalogue No: abx010372
Price:
US$420.50
(Size: 100 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3), with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.
Research Articles on RAC-Gamma Serine/threonine-Protein Kinase (Akt3)
| Target | RAC-Gamma Serine/threonine-Protein Kinase (Akt3) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of Akt3 expressed in E. coli. |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y243 (UniProt, ExPASy) |
| UniProt Secondary AC | Q0VAA6, Q5VTI1, Q5VTI2, Q96QV3, Q9UFP5 |
| UniProt Entry Name | AKT3_HUMAN |
| Gene Symbol | AKT3 |
| GeneID | 10000 |
| OMIM | 611223 |
| HGNC | 393 |
| Ensembl | ENSG00000117020 |
| String | 9606.ENSP00000263826 |
| Enzyme Commission Number | EC 2.7.11.1 EC 2.7.11 |
| Molecular Weight | 55 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |