RAC-Gamma Serine/threonine-Protein Kinase (AKT3) Antibody

AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).

Target	RAC-Gamma Serine/threonine-Protein Kinase (AKT3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat, Monkey
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 88-118 amino acids from the Central region of human AKT3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y243 (UniProt, ExPASy)
UniProt Secondary AC	Q0VAA6, Q5VTI1, Q5VTI2, Q96QV3, Q9UFP5
UniProt Entry Name	AKT3_HUMAN
String	9606.ENSP00000263826
Enzyme Commission Number	EC 2.7.11.1 EC 2.7.11
Molecular Weight	Calculated MW: 55.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on RAC-Gamma Serine/threonine-Protein Kinase (AKT3)

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