+44 (0) 1223 755950
+1 832 327 7413
Aminolevulinate Delta Synthase 1 (ALAS1) Antibody
REQUEST MORE INFO
Catalogue No: abx005001
Price:
US$348.00
(Size: 60 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
ALAS1 Antibody is a Rabbit Polyclonal antibody against ALAS1. This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Research Articles on Aminolevulinate Delta Synthase 1 (ALAS1)
| Target | Aminolevulinate Delta Synthase 1 (ALAS1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human ALAS1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P13196 (UniProt, ExPASy) |
| UniProt Entry Name | HEM1_HUMAN |
| Gene Symbol | ALAS1 |
| GeneID | 211 |
| NCBI Accession | NP_954635.1 |
| KEGG | hsa:211 |
| String | 9606.ENSP00000378416 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |