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Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody
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Catalogue No: abx027971
Price:
US$326.25
(Size: 80 µl)
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ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
Research Articles on Aldehyde Dehydrogenase, Mitochondrial (ALDH2)
| Target | Aldehyde Dehydrogenase, Mitochondrial (ALDH2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 318-347 amino acids from the Central region of human ALDH2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P05091 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DW54, E7EUE5, Q03639, Q6IB13, Q6IV71 |
| UniProt Entry Name | ALDH2_HUMAN |
| NCBI Accession | NP_000681.2 NP_001191818.1 |
| KEGG | hsa:217 |
| String | 9606.ENSP00000261733 |
| Molecular Weight | Calculated MW: 56.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat ALDH2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |