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Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1) Antibody
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Catalogue No: abx025199
Price:
US$326.25
(Size: 80 µl)
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This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Research Articles on Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1)
| Target | Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25, IF/ICC: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human ALDH6A1 recombinant protein. |
| Isotype | IgG1 Kappa |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q02252 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R609, B4DFS8, J3KNU8, Q9UKM8 |
| UniProt Entry Name | MMSA_HUMAN |
| NCBI Accession | NP_005580.1 |
| KEGG | hsa:4329 |
| String | 9606.ENSP00000450436 |
| Molecular Weight | Calculated MW: 57.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |