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Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1) Antibody
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Catalogue No: abx002356
Price:
US$203.00
(Size: 20 µl)
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ALDH6A1 Antibody is a Rabbit Polyclonal antibody against ALDH6A1. This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.
Research Articles on Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1)
| Target | Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 326-535 of human ALDH6A1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q02252 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R609, B4DFS8, J3KNU8, Q9UKM8 |
| UniProt Entry Name | MMSA_HUMAN |
| Gene Symbol | ALDH6A1 |
| GeneID | 4329 |
| NCBI Accession | NP_005580.1 |
| KEGG | hsa:4329 |
| String | 9606.ENSP00000450436 |
| Molecular Weight | Calculated MW: 58 kDa Observed MW: 58 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |