Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1) Antibody

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Catalogue No: abx002356
Price: US$348.00
(Size: 60 µl)

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Datasheet SDS
ALDH6A1 Antibody is a Rabbit Polyclonal antibody against ALDH6A1. This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.

Target Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications IF/ICC
Host Rabbit
Recommended dilutions IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein corresponding to human ALDH6A1
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q02252 (UniProt, ExPASy)
UniProt Secondary AC B2R609, B4DFS8, J3KNU8, Q9UKM8
UniProt Entry Name MMSA_HUMAN
Gene Symbol ALDH6A1
GeneID 4329
NCBI Accession NP_005580.1
KEGG hsa:4329
String 9606.ENSP00000450436
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1)


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