+44 (0) 1223 755950
+1 832 327 7413
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) Antibody
REQUEST MORE INFO
Catalogue No: abx147721
Price:
US$406.00
(Size: 100 µg)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) Antibody is a Rabbit Polyclonal antibody for the detection of AKR1C2. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
Research Articles on Aldo-Keto Reductase Family 1 Member C2 (AKR1C2)
| Target | Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Aldo-keto reductase family 1 member C2 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P52895 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K2N9, B4DKR9, Q14133, Q5SR16, Q7M4N1, Q96A71 |
| UniProt Entry Name | AK1C2_HUMAN |
| Gene Symbol | AKR1C2 |
| GeneID | 1646 |
| OMIM | 600450 |
| HGNC | 385 |
| KEGG | hsa:1646 |
| Ensembl | ENSG00000151632 |
| String | 9606.ENSP00000370129 |
| Enzyme Commission Number | EC 1.-.-.- EC 1.1.1.213 EC 1.3.1.20 |
| Molecular Weight | Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |