Fructose-Bisphosphate Aldolase A (ALDOA) Antibody

Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1, 6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.

Target	Fructose-Bisphosphate Aldolase A (ALDOA)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 303-331 amino acids from the C-terminal region of human ALDOA.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P04075 (UniProt, ExPASy)
UniProt Secondary AC	B4DXI7, Q6FH76, Q6FI10, Q96B15, Q9BWD9, Q9UCN2
UniProt Entry Name	ALDOA_HUMAN
Gene Symbol	ALDOA
GeneID	226
OMIM	103850
HGNC	414
KEGG	hsa:226
Ensembl	ENSG00000149925
String	9606.ENSP00000378669
Molecular Weight	Calculated MW: 39.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rabbit ALDOA.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fructose-Bisphosphate Aldolase A (ALDOA)

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