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ALG11, Alpha-1,2-Mannosyltransferase (ALG11) Antibody
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Catalogue No: abx028386
Price:
US$290.00
(Size: 80 µl)
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This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1, 2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1, 2-mannosyltransferase has been identified on chromosome 19.
Research Articles on ALG11, Alpha-1,2-Mannosyltransferase (ALG11)
| Target | ALG11, Alpha-1,2-Mannosyltransferase (ALG11) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human ALG11. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q2TAA5 (UniProt, ExPASy) |
| UniProt Secondary AC | A5PLP3, B4DKW9, Q5TAN9, Q6DKI6, Q96FI7 |
| UniProt Entry Name | ALG11_HUMAN |
| KEGG | hsa:440138 |
| String | 9606.ENSP00000430236 |
| Molecular Weight | Calculated MW: 55.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |