Alpha Synuclein Phospho-Ser129 (SNCA pS129) Antibody (FITC)

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Catalogue No: abx451881
Price: US$899.00
(Size: 100 µg)

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Datasheet SDS
Alpha Synuclein Phospho-Ser129 (SNCA pS129) Antibody (FITC) is a rabbit monoclonal antibody against Alpha Synuclein Phospho-Ser129 (SNCA pS129). Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].

Target Alpha Synuclein Phospho-Ser129 (SNCA pS129)
Clonality Monoclonal
Target Modification Ser129
Modification Phosphorylation
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation FITC
Immunogen Human alpha synuclein AA 124-134: AYEMP-pS-EEGYQ-Cys.
Isotype IgG
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P37840 (UniProt, ExPASy)
UniProt Secondary AC A8K2A4, Q13701, Q4JHI3, Q6IAU6
UniProt Entry Name SYUA_HUMAN
Gene Symbol SNCA
GeneID 6622
OMIM 163890
NCBI Accession NP_000336.1
HGNC 11138
KEGG hsa:6622
String 9606.ENSP00000338345
Buffer PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Specificity Binds to phosphorylated serine 129 on alpha synuclein. Does not detect unphosphorylated serine 129 alpha synuclein.
Concentration 1 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Alpha Synuclein Phospho-Ser129 (SNCA pS129)


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