Alpha Synuclein Phospho-Ser129 (SNCA pS129) Antibody (HRP)

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Catalogue No: abx451882
Price: US$884.50
(Size: 100 µg)

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Datasheet SDS
Alpha Synuclein Phospho-Ser129 (SNCA pS129) Antibody (HRP) is a rabbit monoclonal antibody against Alpha Synuclein Phospho-Ser129 (SNCA pS129). Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].

Target Alpha Synuclein Phospho-Ser129 (SNCA pS129)
Clonality Monoclonal
Target Modification Ser129
Modification Phosphorylation
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation HRP
Immunogen Human alpha synuclein AA 124-134: AYEMP-pS-EEGYQ-Cys.
Isotype IgG
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P37840 (UniProt, ExPASy)
UniProt Secondary AC A8K2A4, Q13701, Q4JHI3, Q6IAU6
UniProt Entry Name SYUA_HUMAN
Gene Symbol SNCA
GeneID 6622
OMIM 163890
NCBI Accession NP_000336.1
HGNC 11138
KEGG hsa:6622
String 9606.ENSP00000338345
Buffer PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Specificity Binds to phosphorylated serine 129 on alpha synuclein. Does not detect unphosphorylated serine 129 alpha synuclein.
Concentration 1 mg/ml
Availability Shipped within 5-12 working days.
Note This product is for research use only.
Research Articles on Alpha Synuclein Phospho-Ser129 (SNCA pS129)


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