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Alkaline Phosphatase, Placental Type (ALPP) Antibody
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Catalogue No: abx011923
Price:
US$420.50
(Size: 100 µl)
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There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The exact physiological function of the alkaline phosphatases is not known. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Research Articles on Alkaline Phosphatase, Placental Type (ALPP)
| Target | Alkaline Phosphatase, Placental Type (ALPP) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human ALPP expressed in E. coli. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P05187 (UniProt, ExPASy) |
| UniProt Secondary AC | P05188, P06861, Q53S78, Q96DB7 |
| UniProt Entry Name | PPB1_HUMAN |
| Gene Symbol | ALPP |
| GeneID | 250 |
| OMIM | 171800 |
| HGNC | 439 |
| KEGG | hsa:250 |
| Ensembl | ENSG00000163283 |
| String | 9606.ENSP00000375881 |
| Enzyme Commission Number | EC 3.1.3.1 |
| Molecular Weight | 58 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |