Homeobox Protein Aristaless-Like 4 (ALX4) Antibody

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2) ; an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del (11) (p11p12), causes Potocki-Shaffer syndrome (PSS) ; a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq].

Target	Homeobox Protein Aristaless-Like 4 (ALX4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 249-275 amino acids from the Central region of human ALX4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9H161 (UniProt, ExPASy)
UniProt Secondary AC	Q96JN7, Q9H198, Q9HAY9
UniProt Entry Name	ALX4_HUMAN
Gene Symbol	ALX4
String	9606.ENSP00000332744
Molecular Weight	Calculated MW: 44.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Cow ALX4.
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Homeobox Protein Aristaless-Like 4 (ALX4)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue