+44 (0) 1223 755950
+1 832 327 7413
Alpha-Methylacyl-CoA Racemase (AMACR) Antibody
REQUEST MORE INFO
Catalogue No: abx001044
Price:
US$348.00
(Size: 60 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
AMACR Antibody is a Rabbit Polyclonal antibody against AMACR. This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Research Articles on Alpha-Methylacyl-CoA Racemase (AMACR)
| Target | Alpha-Methylacyl-CoA Racemase (AMACR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human AMACR |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UHK6 (UniProt, ExPASy) |
| UniProt Entry Name | AMACR_HUMAN |
| Gene Symbol | AMACR |
| GeneID | 23600 |
| NCBI Accession | NP_055139.4 |
| String | 9606.ENSP00000371517 |
| Molecular Weight | Calculated MW: 22 kDa/25 kDa/42 kDa/43 kDa Observed MW: 43 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |