AMOT (pY599) Antibody

This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	AMOT (pY599)
Clonality	Polyclonal
Target Modification	Tyr599
Modification	Phosphorylation
Reactivity	Human
Tested Applications	ELISA, DB
Host	Rabbit
Recommended dilutions	DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y599 of human AMOT.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q4VCS5 (UniProt, ExPASy)
UniProt Secondary AC	Q504X5, Q9HD27, Q9UPT1
UniProt Entry Name	AMOT_HUMAN
KEGG	hsa:154796
String	9606.ENSP00000361027
Molecular Weight	Calculated MW: 118 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse AMOT.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on AMOT (pY599)

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